Overcoming Onychomycosis™ By Scott Davis If you want a natural and proven solution for onychomycosis, you should not look beyond Overcoming Onychomycosis. It is easy to follow and safe as well. You will not have to take drugs and chemicals. Yes, you will have to choose healthy foods to treat your nail fungus. You can notice the difference within a few days. Gradually, your nails will look and feel different. Also, you will not experience the same condition again!
What are the standard treatments for onychomycosis?
Routine onychomycosis (fungal nail infection) treatments can be categorized into three: oral antifungals, topical antifungals, and procedure. This is the breakdown:
1. Oral Antifungal Medications (Systemic Therapy)
These are generally the most effective, especially for more severe infections.
Terbinafine (Lamisil) – Usually daily for 6 weeks (fingernails) or 12 weeks (toenails).
Itraconazole (Sporanox) – Typically taken in pulses (1 week every month for 2–3 months).
Fluconazole (Diflucan) – Off-label, usually weekly for a few months.
✅ Pros: More effective, cures the infection from inside out.
⚠️ Cons: Potential liver toxicity (blood work may be needed), drug interactions.
2. Topical Antifungal Therapies
Best for early or minor infection or those who are unable to take pills.
Efinaconazole (Jublia) – 48 weeks daily.
Tavaborole (Kerydin) – 48 weeks daily.
Ciclopirox (Penlac) – A daily lacquer.
✅ Pros: Fewer systemic side effects.
⚠️ Cons: Must be used rigorously daily; lower effectiveness, especially with thick nails.
3. Procedural or Physical Therapies
Can be employed alone or in conjunction with medication.
Laser therapy – FDA-cleared equipment (e.g., PinPointe) heat and destroy fungi. Inconsistent evidence of effectiveness.
Debridement – Removal, filing, or surgical excision of thickened or infected areas of the nail.
Surgical removal of the nail – In extreme, unusual situations, the nail is removed completely.
Combination Therapy
Oral + topical combinations tend to increase cure rates, especially in resistant cases.
Prevention after failure
Dry and clean the feet.
Socks and shoes changed regularly.
Use of antifungal powders or sprays.
Avoid walking barefoot in public (swimming pools, gyms).
Would you like a treatment comparison chart or advice on how to choose the right one?
Antifungal medications treat onychomycosis (fungal nail infection) by destroying the fungal pathogens responsible for the infection, typically dermatophytes, yeasts, or non-dermatophyte molds. Antifungal medications work in one or more of the following processes:
1. Preventing Formation of Fungal Cell Membranes
Most antifungal medications (notably azoles and allylamines) prevent the formation of ergosterol, a component of fungal cell membranes. With no ergosterol, the membrane is unstable and leaky, ultimately causing the death of the fungus.
Allylamines (e.g., terbinafine):
Interfere with squalene epoxidase, an ergosterol biosynthesis pathway enzyme.
Resulting in toxic squalene accumulation and reduction in ergosterol content.
Azoles (e.g., itraconazole):
Inhibit lanosterol 14α-demethylase, another enzyme necessary to synthesize ergosterol.
2. Disrupting Cell Wall Synthesis
Some topical agents, such as ciclopirox, inhibit nutrient absorption and slow down metabolic processes, leading to cell death.
3. Direct Fungicidal Activity
Certain agents (e.g., amorolfine) alter the structure of the fungal membrane and inhibit a number of enzymes involved in the biosynthesis of ergosterol, making them broadly fungicidal.
Delivery and Treatment Considerations:
Oral antifungals (e.g., terbinafine and itraconazole) are more effective for widespread or serious infections because they penetrate to the nail bed through the blood.
Topical antifungals are used for mild to moderate infections, especially when the matrix is not involved.
Treatment is prolonged: typically 6–12 weeks with oral therapy, but nails take several months to appear normal because they grow slowly.
Would you like a side-by-side comparison chart of the most frequent antifungal medications for onychomycosis?
Overcoming Onychomycosis™ By Scott Davis If you want a natural and proven solution for onychomycosis, you should not look beyond Overcoming Onychomycosis. It is easy to follow and safe as well. You will not have to take drugs and chemicals. Yes, you will have to choose healthy foods to treat your nail fungus. You can notice the difference within a few days. Gradually, your nails will look and feel different. Also, you will not experience